Brain and behavior: Evidences of neuroimaging and neuropsychological testing in Alzheimer’s Disease pathology.
Keywords:
Keywords: Neuropsychology, Neuroimaging, Neurodegeneration, Cognitive impairment, Alzheimer’s Disease., Highlights Neuroimaging techniques can quantify changes in neurometabolites in brain diseases. Neuropsychological tests provide cognitive profile to understand brain deficits. Brain Autopsy and In vivo studies of neurodegenerative diseases are discussed. Correlation indicated an early predictive model of cognitive decline in AD. These changes are also seen in different psychiatric disorders.Abstract
Abstract:
The impairment in cognitive functions is an important indicator in neurodegenerative disease. Both in-vitro and in vivo studies indicates that various neurochemical activities in the brain seems to play an important role in the disease etiology. Along with neuroimaging, neuropsychological tests are done to identify the nature of cognitive deficits. These are performance-based measures of individual’s cognitive capacities. Studying brain region specific alteration of these neurochemicals along with specific neuropsychological tests in can provide an insight towards diagnosis, progression pattern, response towards treatment functional potential and prognosis. This article aims to highlight the importance of neuropsychological testing in neurodegeneration as strong diagnostic indicator collaborating the literature based findings with different neuroimaging techniques.
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